You can download the notes of Unit 3 of B pharm 1st year 1st semester subject Bp 104T inorgenic Chemistry from here
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In Unit 3, you have to study all these
- Gastro Intestinal agents
- Gastrointestinal tract (GIT)
- Acidifying agents/Acidifiers
- Types of Acidifying agents/Acidifiers
- Antacids
- Classification ofAntacids
- Magnesium Hydroxide Oral Suspension
- Cathartics
- Magnesium Sulphate
- Sodium Orthophosphate
- Kaolin
- Bentonite
- ANTI-MICROBIAL AGENTS
- Potassium Permanganate
- Boric Acid
- Hydrogen Peroxide
- Chlorinated lime
- Iodine
Gastro Intestinal agents
In this, you will find acidifiers, anta acid, antimicrobials and cathartics, laxatives and Purgative are going to read this topic
Gastrointestinal tract (GIT)
The gastro intestinal tract ( GIT ) is the tract
Or passageway of the digestive system that leads from the mouth to the anus (ingestion
of food to the expulsion of waste or faeces.)
The GI tract contains all the major organs of the digestive system,
- Esophagus
- Stomach
- intestine
- Rectum
Acidifying agents
Acidifying agents/acidifiers are used in a condition when there is absence or insufficient secretion of hydrochloric.
acid in stomach, which leads to a disease called achlorhydria or hypochlorhydria.
These are used to increase the level of gastric acid in stomach.
The pH of stomach is 1.5-2 when empty and rises to pH 5-6 when food is ingested.
There are mainly three types of acidifiers
- Gastric acidifiers
- Urinary acidifiers
- Systemic acidifiers
Gastric acidifiers: they are the drugs which are used to increase acidity of the stomach in the patients suffering from achlorhydria or hypochlorhydria.
Urinary acidifiers: they are the drugs which are used to remove acidic urine from the body or to maintain the pH of urine. These are
Widely used to cure some types of urinary tract infections (UTIs)
Systemic acidifiers: they are the drugs which are used to neutralize the alkaline body fluid and control the pH of all parts of the body they are used to treat patients suffering from alkalosis.
What is Antacid?
Antacids (anti - against; acidus - acid) are alkaline substances used to neutralize hydrochloric acid in the stomach.
Gives symptomatic relief of pain due to hyperchlorhydria.
Antacids are the substances which reduce gastric acidity resulting in an increase in the pH of stomach and duodenum.
Gastric acidity occurs due to excessive secretion of HCl in stomach due to various reasons-
Gastritis (Ageneral inflammation of gastric mucosa)
Peptic ulcer or oesophageal ulcer (Lower end of oesophagus)
Duodenum ulcer
Gastric ulcer (Stomach)
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Classification of antacids
- Systemic antacids
- Non-systemic antacid
Systemic antacids
• These antacids get absorbed systemically.
These are highly soluble and potent
neutralizer.
• These are not suitable for the treatment of
peptic ulcer because of risk of ulcer
perforation which can occur due to
production of carbon dioxide in stomach.
e. g. Sodium carbonate.
Non-systemic antacid
These are insoluble and poorly absorbed.
systemically. e. g. Magnesium and
aluminum salts